Genetic Studies
State-of-the-art genetics laboratory supporting advanced genetic studies, offering comprehensive solutions for cutting-edge research and personalized medicine.
Turkey's First Clinical Trial-Dedicated Genetics Laboratory
Established in 2019, Omega Genetics is Turkey's first and only dedicated clinical trial genetics laboratory. Our state-of-the-art facility provides comprehensive genomic and molecular analysis services specifically designed to support clinical research, biomarker discovery, and the growing field of personalized medicine.
Our integrated approach combines next-generation sequencing (NGS), whole-genome and whole-exome sequencing (WGS/WES), targeted gene panels, and liquid biopsy technologies with expert bioinformatics support. We translate complex genetic data into clinically meaningful outcomes that support patient stratification, companion diagnostic development, and regulatory submissions.
All workflows are validated under GCLP (Good Clinical Laboratory Practice) and ICH-GCP guidelines, with ALCOA+ data integrity principles ensuring audit-ready, regulatory-grade results accepted by FDA, EMA, and TİTCK.
Sequencing & Molecular Analysis Platform
NGS / WGS / WES
Whole-genome sequencing, whole-exome sequencing, and targeted gene panels for germline and somatic variant detection with clinical-grade coverage.
RNA Sequencing
Bulk RNA-seq and single-cell RNA-seq for gene expression profiling, fusion gene detection, and transcriptome-based biomarker discovery.
Liquid Biopsy / ctDNA
Circulating tumor DNA analysis for minimal residual disease (MRD) monitoring, treatment response assessment, and resistance mutation detection.
Sanger & MLPA
Sanger sequencing for variant confirmation and MLPA for copy number variation (CNV) detection — gold-standard orthogonal validation methods.
Pharmacogenomics
CYP450 panel, HLA typing, drug metabolism genotyping, and pharmacogenomic profiling for personalized dosing and adverse event prediction.
Bioinformatics & CDx
In-house bioinformatics pipeline for variant calling, annotation (ACMG/AMP), and companion diagnostic (CDx) assay development and validation.
Clinical Trial Applications
Application Scenarios in the Omega Ecosystem
How the Omega Research Ecosystem amplifies genetic studies with direct integration between Omega Genetics, Biorepository, and diagnostic kit infrastructure.
Omega Care
Home Genetic Sample Collection
Home-based buccal swab, saliva, and dried blood spot (DBS) collection for decentralized genetic testing, enabling remote patient enrollment without clinic visits.
Omega Genetics
Direct NGS & WGS Integration
Omega Genetics provides direct NGS, WGS/WES, liquid biopsy, pharmacogenomics, and companion diagnostic development with GCLP-validated workflows and expert bioinformatics.
HelixLab
Pre-Analytical Standardization
Centralized sample receipt, DNA/RNA extraction, and quality control under ISO 17025 protocols before transfer to Omega Genetics for sequencing analysis.
Omega Bio
Companion Dx Kit Development
Kit-based molecular diagnostic infrastructure for companion diagnostic assay development, validation, and manufacturing alignment for clinical trial deployment.
Omega Biorepository
DNA/RNA Long-Term Archive
Multi-decade DNA, RNA, and tissue biobanking at -80C/LN2 with ISBER-aligned chain-of-custody enabling future re-analysis as new variants and biomarkers are discovered.
Animal Facility
Transgenic Animal Models
Genetically modified animal models (knockout, knock-in, transgenic) for preclinical evaluation of gene therapies, genetic drug targets, and inherited disease mechanisms.
Unlock the Power of Genomic Data in Your Clinical Research
Partner with Turkey's first clinical trial-dedicated genetics laboratory.
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